Sequence-specific assembly of Ftsk hexamers establishes directional translocation on DNA

FtsK is a homohexameric, RecA-like dsDNA translocase that plays a key role in bacterial chromosome segregation. The FtsK regulatory γ-subdomain determines directionality of translocation through its interaction with specific 8 base pair chromosomal sequences [(KOPS); FtsK Orienting / Polarizing Sequ...

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Autori principali: Graham, J, Sherratt, D, Szcelkun, M
Natura: Journal article
Lingua:English
Pubblicazione: National Academy of Science of the USA 2010
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