The effect of particle size and electrical charge on macrophage-osteoclast differentiation and bone resorption.
In aseptic loosening, there is commonly periprosthetic bone loss and a heavy macrophage infiltrate in response to biomaterial wear particles generated from the implant materials. Macrophages which have phagocytosed wear particles are known to be capable of differentiation into bone resorbing osteocl...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2003
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