Low-Dose cyclophosphamide induces antitumor T-Cell responses, which associate with survival in metastatic colorectal cancer

<p><strong>Purpose:</strong> Anticancer T-cell responses can control tumors, but immunosuppressive mechanisms in vivo prevent their function. The role of regulatory T cells (Tregs) in metastatic colorectal cancer is unclear. We have previously shown depletion of Tregs enhances col...

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Bibliographic Details
Main Authors: Scurr, M, Pembroke, T, Bloom, A, Roberts, D, Thomson, A, Smart, K, Bridgeman, H, Adams, R, Brewster, A, Jones, R, Gwynne, S, Blount, D, Harrop, R, Hills, R, Gallimore, A, Godkin, A
Format: Journal article
Language:English
Published: American Association for Cancer Research 2017