Cell cycle switch to endocycle: the nucleolus lends a hand.
The bHLH transcription factor Hand1 is essential for placentation and cardiac morphogenesis but how its developmental activity is regulated is largely unknown. We recently showed that Hand1 is sequestered in the nucleoli of rodent trophoblast stem (TS) cells by the I-mfa domain-containing protein HI...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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