Linkage disequilibrium mapping via cladistic analysis of single-nucleotide polymorphism haplotypes.

We present a novel approach to disease-gene mapping via cladistic analysis of single-nucleotide polymorphism (SNP) haplotypes obtained from large-scale, population-based association studies, applicable to whole-genome screens, candidate-gene studies, or fine-scale mapping. Clades of haplotypes are t...

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Bibliographic Details
Main Authors: Durrant, C, Zondervan, K, Cardon, L, Hunt, S, Deloukas, P, Morris, A
Format: Journal article
Language:English
Published: 2004