Delayed repair of radiation induced clustered DNA damage: friend or foe?

A signature of ionizing radiation exposure is the induction of DNA clustered damaged sites, defined as two or more lesions within one to two helical turns of DNA by passage of a single radiation track. Clustered damage is made up of double strand breaks (DSB) with associated base lesions or abasic (...

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Bibliographic Details
Main Authors: Eccles, L, O'Neill, P, Lomax, M
Format: Journal article
Language:English
Published: 2011