Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach

The World Health Organization has a goal of universal drug susceptibility testing for patients with tuberculosis; however, molecular diagnostics to date have focused largely on first-line drugs and predicting binary susceptibilities. We used a multivariable linear mixed model alongside whole genome...

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Bibliographic Details
Main Authors: Barilar, I, Battaglia, S, Borroni, E, Zankin, A, Clifton, D, Crook, D, Earle, S, Fowler, PW, Giberto Cruz, A, Hoosdally, S, Knaggs, J, Hunt, M, Kouchaki, S, Lachapelle, A, Peto, T, Rodger, G, Roohi, A, Thwaites, G, Walker, AS, Wilson, D, Yang, Y
Other Authors: Cryptic Consortium
Format: Journal article
Language:English
Published: Springer Nature 2024