The human cytochrome P-450 21-hydroxylase genes
<p>Deficiency of the cytochrome P-450 steroid 21-hydroxylase (21-OHase) which causes Congenital Adrenal Hyperplasia (CAH) is a monogenic autosomal recessive disorder which is linked to HLA. There are two 21-OHase genes in man, A and B, and they are mapped to the HLA class III region ~ 3 kb 3&...
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| Format: | Thesis |
| Language: | English |
| Published: |
1987
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| Subjects: |