Review. SUR1: a unique ATP-binding cassette protein that functions as an ion channel regulator.

SUR1 is an ATP-binding cassette (ABC) transporter with a novel function. In contrast to other ABC proteins, it serves as the regulatory subunit of an ion channel. The ATP-sensitive (KATP) channel is an octameric complex of four pore-forming Kir6.2 subunits and four regulatory SUR1 subunits, and it l...

תיאור מלא

מידע ביבליוגרפי
Main Authors: Aittoniemi, J, Fotinou, C, Craig, T, De Wet, H, Proks, P, Ashcroft, F
פורמט: Journal article
שפה:English
יצא לאור: 2009