Large scale meta-analysis of urinary C-terminal telopeptide, serum cartilage oligomeric protein and matrix metalloprotease degraded type II collagen and their role in prevalence, incidence and progression of osteoarthritis.

OBJECTIVE: To evaluate the role of three cartilage-derived biomarkers on osteoarthritis (OA): urinary C-terminal telopeptide (uCTX-II), serum cartilage oligomeric protein (sCOMP), and serum MMP degraded type II collagen (sC2M). SUBJECTS AND METHODS: Samples from 3582 individuals from the Rotterdam S...

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Main Authors: Valdes, A, Meulenbelt, I, Chassaing, E, Arden, N, Bierma-Zeinstra, S, Hart, D, Hofman, A, Karsdal, M, Kloppenburg, M, Kroon, H, Slagboom, E, Spector, T, Uitterlinden, A, van Meurs, J, Bay-Jensen, A
Format: Journal article
Language:English
Published: W.B. Saunders Ltd 2014