Enantioselective organocatalytic aldol reaction of ynones and its synthetic applications.

Enantioselective organocatalytic aldol reaction of ynones and its synthetic applications.

[Structure: see text] For the first time, unmodified ynones were used in organocatalytic asymmetric aldol reactions delivering monoprotected anti-alpha,beta-dihydroxyynones in high yields, dr's up to 19:1, and ee's up to 95%. These products can be either reduced to afford enantioenriched u...

Полное описание

Библиографические подробности
Главные авторы:	Silva, F, Sawicki, M, Gouverneur, V
Формат:	Journal article
Язык:	English
Опубликовано:	2006

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