Tuftsin derivatives of FITC, Tb-DOTA or Gd-DOTA as potential macrophage-specific imaging biomarkers.

Fluorescein- and terbium-labelled tuftsin (Thr-Lys-Pro-Arg) and pentapeptide (Thr-Lys-Pro-Pro-Arg) were synthesized and their properties were evaluated in vitro by luminescence spectrometry and confocal microscopy as fluorescence probes to target macrophage cells in biological systems. An increase i...

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Bibliographic Details
Main Authors: Feng, J, Meloni, M, Allan, S, Faulkner, S, Narvainen, J, Vidyasagar, R, Kauppinen, R
Format: Journal article
Language:English
Published: 2010