Dampened inflammatory signalling and myeloid-derived suppressor-like cell accumulation reduces circulating monocytic HLA-DR density and may associate with malignancy risk in long-term renal transplant recipients

Background: Malignancy is a major cause of morbidity and mortality in transplant recipients. Identification of those at highest risk could facilitate pre-emptive intervention such as reduction of immunosuppression. Reduced circulating monocytic HLA-DR density is a marker of immune depression in the...

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Bibliographic Details
Main Authors: Bottomley, MJ, Harden, PN, Wood, KJ, Hester, J, Issa, F
Format: Journal article
Language:English
Published: Frontiers Media SA 2022