Dampened inflammatory signalling and myeloid-derived suppressor-like cell accumulation reduces circulating monocytic HLA-DR density and may associate with malignancy risk in long-term renal transplant recipients
Background: Malignancy is a major cause of morbidity and mortality in transplant recipients. Identification of those at highest risk could facilitate pre-emptive intervention such as reduction of immunosuppression. Reduced circulating monocytic HLA-DR density is a marker of immune depression in the...
Main Authors: | Bottomley, MJ, Harden, PN, Wood, KJ, Hester, J, Issa, F |
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Format: | Journal article |
Language: | English |
Published: |
Frontiers Media SA
2022
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