Validation of a multiplexed immunoassay for immunological analysis of pre erythrocytic malaria vaccines

The primary immunological readout for clinical trials of R21/MatrixM™ malaria vaccine, is total IgG antibody specific to the central four amino acid NANP repeat region of the circumsporozoite protein. A multiplexed assay, which includes NANP, was developed and validated for four antigens representin...

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Bibliographic Details
Main Authors: Stockdale, LK, Provstgaard-Morys, S, Bellamy, D, Woods, D, Rapi, K, Bajer, A, Hollingdale, B, Muñoz, O, Malik, S, Hill, AVS, Ewer, KJ
Format: Journal article
Language:English
Published: Nature Research 2025