Investigating the role of homologous recombination at human centromeres

<p>Centromeres are structurally essential regions of the eukaryotic genome, acting as platforms for kinetochore establishment and microtubule attachment during chromosome segregation. Despite their essential function, centromeres are implicated during genome instability, as DNA breaks and rear...

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Bibliographic Details
Main Author: Saayman, X
Other Authors: Esashi, F
Format: Thesis
Language:English
Published: 2022