MRE11-RAD50-NBS1 complex disassembly from DNA double-strand breaks after ionising radiation
<p>The complex formed by MRE11 –RAD50 and –NBS1, designated the MRN complex is essential for the DNA damage response (DDR). The MRN complex has a well-studied role in DNA end resection as part of the homologous recombination (HR) pathway. HR repairs double-strand breaks (DSB), the most toxic l...
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| Format: | Thesis |
| Language: | English |
| Published: |
2022
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