Hydroxylation of the eukaryotic ribosomal decoding center affects translational accuracy.

The mechanisms by which gene expression is regulated by oxygen are of considerable interest from basic science and therapeutic perspectives. Using mass spectrometric analyses of Saccharomyces cerevisiae ribosomes, we found that the amino acid residue in closest proximity to the decoding center, Pro-...

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Bibliographic Details
Main Authors: Loenarz, C, Sekirnik, R, Thalhammer, A, Ge, W, Spivakovsky, E, Mackeen, M, McDonough, M, Cockman, M, Kessler, B, Ratcliffe, P, Wolf, A, Schofield, C
Format: Journal article
Language:English
Published: National Academy of Sciences 2014