Interaction of the leucine-rich repeats of polycystin-1 with extracellular matrix proteins: possible role in cell proliferation.
Polycystin-1, the product of the PKD1 gene, is a membrane-bound multidomain protein with a unique structure and a molecular weight of approximately 460 kD. The purpose of this study is to investigate the binding of the cystein-flanked leucine-rich repeats (LRR) of polycystin-1 to extracellular matri...
Hlavní autoři: | Malhas, A, Abuknesha, R, Price, R |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2002
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