Role of Neisseria meningitidis luxS in cell-to-cell signaling and bacteremic infection.

Numerous pathogenic bacteria contain luxS, which is required for autoinducer-2 production. Here, we demonstrate that Neisseria meningitidis contains a functional copy of luxS that is necessary for full meningococcal virulence; strains with a luxS deletion are defective for bacteremia, a prerequisite...

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Bibliographic Details
Main Authors: Winzer, K, Sun, Y, Green, A, Delory, M, Blackley, D, Hardie, K, Baldwin, T, Tang, C
Format: Journal article
Language:English
Published: 2002