Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children.
Humans respond to foreign antigen by generating plasma Abs and memory B cells (MBCs). The Ab response then declines, sometimes to below the limit of detection. In contrast, MBCs are generally thought to be long-lived. We tested and compared Plasmodium falciparum (Pf)-specific Ab and MBC responses in...
Main Authors: | , , , , , , , , |
---|---|
פורמט: | Journal article |
שפה: | English |
יצא לאור: |
2012
|