Memory B cells are a more reliable archive for historical antimalarial responses than plasma antibodies in no-longer exposed children.
Humans respond to foreign antigen by generating plasma Abs and memory B cells (MBCs). The Ab response then declines, sometimes to below the limit of detection. In contrast, MBCs are generally thought to be long-lived. We tested and compared Plasmodium falciparum (Pf)-specific Ab and MBC responses in...
Main Authors: | Ndungu, F, Olotu, A, Mwacharo, J, Nyonda, M, Apfeld, J, Mramba, L, Fegan, G, Bejon, P, Marsh, K |
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Format: | Journal article |
Jezik: | English |
Izdano: |
2012
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