Intestinal epithelial cell autophagy is required to protect against TNF-induced apoptosis during chronic colitis in mice

Genome-wide association studies have linked polymorphisms in the autophagy gene ATG16L1 with susceptibility to inflammatory bowel disease (IBD). However, the cell-type-specific effects of autophagy on the regulation of chronic intestinal inflammation have not been investigated. Here, we assessed the...

詳細記述

書誌詳細
主要な著者: Pott, J, Kabat, A, Maloy, K
フォーマット: Journal article
言語:English
出版事項: Cell Press 2018