Efficient in vivo transfection and safety profile of a CpG-free and codon optimized luciferase plasmid using a cationic lipophosphoramidate in a multiple intravenous administration procedure

<p>As any drug, the success of gene therapy is largely dependent on the vehicle that has to selectively and efficiently deliver therapeutic nucleic acids into targeted cells with minimal side-effects. In the case of chronic diseases that require a life-long treatment, non-viral gene delivery v...

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Bibliographic Details
Main Authors: Lindberg, MF, Le Gall, T, Carmoy, N, Berchel, M, Hyde, SC, Gill, D, Jaffrès, P, Lehn, P, Montier, T
Format: Journal article
Language:English
Published: Elsevier 2015