The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases.
The regulatory fragment of Src kinases, comprising Src homology (SH) 3 and SH2 domains, is responsible for controlled repression of kinase activity. We have used a multidisciplinary approach involving crystallography, NMR, and isothermal titration calorimetry to study the regulatory fragment of Fyn...
Main Authors: | , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2001
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