The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases.

The regulatory fragment of Src kinases, comprising Src homology (SH) 3 and SH2 domains, is responsible for controlled repression of kinase activity. We have used a multidisciplinary approach involving crystallography, NMR, and isothermal titration calorimetry to study the regulatory fragment of Fyn...

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Bibliografski detalji
Glavni autori: Arold, S, Ulmer, T, Mulhern, T, Werner, J, Ladbury, J, Campbell, I, Noble, M
Format: Journal article
Jezik:English
Izdano: 2001