Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants

Most genetic association signals for type 2 diabetes risk are located in non-coding regions of the genome, hindering translation into molecular mechanisms. Physiological studies have shown a majority of disease-associated variants to exert their effects through pancreatic islet dysfunction. Systemat...

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Bibliographic Details
Main Authors: Thomsen, S, Ceroni, A, van de Bunt, M, Burrows, C, Barrett, A, Scharfmann, R, Ebner, D, McCarthy, M, Gloyn, A
Format: Journal article
Language:English
Published: American Diabetes Association 2016