Systematic Functional Characterization of Candidate Causal Genes for Type 2 Diabetes Risk Variants
Most genetic association signals for type 2 diabetes risk are located in non-coding regions of the genome, hindering translation into molecular mechanisms. Physiological studies have shown a majority of disease-associated variants to exert their effects through pancreatic islet dysfunction. Systemat...
Main Authors: | , , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
American Diabetes Association
2016
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