Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells.

The Notch ligand, Dll4, is essential for angiogenesis during embryonic vascular development and is involved in tumour angiogenesis. Several recent publications demonstrated that blockade of Dll4 signalling inhibits tumour growth, suggesting that it may constitute a good candidate for anti-cancer the...

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Bibliographic Details
Main Authors: Harrington, L, Sainson, R, Williams, C, Taylor, J, Shi, W, Li, J, Harris, A
Format: Journal article
Language:English
Published: 2008