Regulation of multiple angiogenic pathways by Dll4 and Notch in human umbilical vein endothelial cells.
The Notch ligand, Dll4, is essential for angiogenesis during embryonic vascular development and is involved in tumour angiogenesis. Several recent publications demonstrated that blockade of Dll4 signalling inhibits tumour growth, suggesting that it may constitute a good candidate for anti-cancer the...
Main Authors: | Harrington, L, Sainson, R, Williams, C, Taylor, J, Shi, W, Li, J, Harris, A |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2008
|
Similar Items
-
The role of DLL4-NOTCH signalling in endothelial cell metabolism
by: Harjes, U
Published: (2014) -
Mechanoresponsive ETS1 causes endothelial dysfunction and arterialization in varicose veins via NOTCH4/DLL4 signaling
by: B.J. Sreelakshmi, et al.
Published: (2024-06-01) -
Dll4/Notch Signaling Pathway and Tumor Angiogenesis
by: Xinyu DING, et al.
Published: (2009-11-01) -
DLL4-Notch signaling mediates tumor resistance to anti-VEGF therapy in vivo.
by: Li, J, et al.
Published: (2011) -
DLL4-Notch Signaling Mediates Tumor Resistance to Anti-VEGF Therapy In Vivo
by: Li, J, et al.
Published: (2011)