A Fluorescence‐based assay for screening β‐lactams targeting the Mycobacterium tuberculosis transpeptidase LdtMt2

Mycobacterium tuberculosis L,D‐transpeptidases (Ldts), which are involved in cell wall biosynthesis, have emerged as promising targets for the treatment of tuberculosis. However, an efficient method for testing inhibition of these enzymes is not currently available. We present a fluorescence‐based a...

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Bibliographic Details
Main Authors: De Munnik, M, Lohans, C, Langley, G, Bon, C, Brem, J, Schofield, C
Format: Journal article
Language:English
Published: Wiley 2019