Mitochondrial dysfunction and mitophagy in Parkinson’s disease: From mechanism to therapy

Mitochondrial dysfunction is implicated in PD through both environmental exposure and genetic factors. Increased understanding of mitochondrial dysfunction and mitophagy in PD has identified new mechanisms and therapeutic opportunities. Identification of the up- and downstream regulators of PINK1/pa...

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Bibliographic Details
Main Authors: Malpartida, AB, Williamson, M, Narendra, DP, Wade-Martins, R, Ryan, BJ
Format: Journal article
Language:English
Published: Cell Press 2020