Identification and characterisation of determinants of genome stability in response to a double-strand break

<p>Chromosomal rearrangements can lead to loss of heterozygosity (LOH) and oncogene activation, both of which represent possible causative events in cancer development. Such outcomes can result from the misrepair of DNA damage arising from a variety of events including DNA double-strand breaks...

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Bibliografski detalji
Glavni autor: Kasparek, TR
Daljnji autori: Humphrey, T
Format: Disertacija
Jezik:English
Izdano: 2013
Teme: