A noncarbohydrate based approach to polyhydroxylated pyrrolidizines: total syntheses of the natural products hyacinthacine A1 and 1-epiaustraline.

[reaction: see text] A flexible route to polyhydroxylated pyrrolizidine alkaloids is described, starting from commercially available N-Boc pyrrole and using a partial reduction as the key step. Tactics for varying the stereochemistry around the ring by choice of partial reduction conditions are disc...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Donohoe, T, Sintim, H, Hollinshead, J
स्वरूप: Journal article
भाषा:English
प्रकाशित: 2005