The chemistry, physiology and pathology of pH in cancer.

Cell survival is conditional on the maintenance of a favourable acid-base balance (pH). Owing to intensive respiratory CO2 and lactic acid production, cancer cells are exposed continuously to large acid-base fluxes, which would disturb pH if uncorrected. The large cellular reservoir of H(+)-binding...

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Detalhes bibliográficos
Principais autores: Swietach, P, Vaughan-Jones, R, Harris, A, Hulikova, A
Formato: Journal article
Idioma:English
Publicado em: 2014