The chemistry, physiology and pathology of pH in cancer.
Cell survival is conditional on the maintenance of a favourable acid-base balance (pH). Owing to intensive respiratory CO2 and lactic acid production, cancer cells are exposed continuously to large acid-base fluxes, which would disturb pH if uncorrected. The large cellular reservoir of H(+)-binding...
Principais autores: | , , , |
---|---|
Formato: | Journal article |
Idioma: | English |
Publicado em: |
2014
|