Pharmacokinetics of co-formulated mefloquine and artesunate in pregnant and non-pregnant women with uncomplicated Plasmodium falciparum infection in Burkina Faso.

OBJECTIVES: Mefloquine/artesunate has recently been developed as a fixed-dose combination, providing a promising rescue/alternative treatment for malaria during pregnancy. However, limited data are available on the effect of pregnancy on its pharmacokinetic properties. This study was conducted to as...

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Detalhes bibliográficos
Principais autores: Valea, I, Tinto, H, Traore-Coulibaly, M, Toe, L, Lindegardh, N, Tarning, J, Van Geertruyden, J, D'Alessandro, U, Davies, G, Ward, SA
Formato: Journal article
Idioma:English
Publicado em: Oxford University Press 2014