Neurotoxicity in lymphoblastic leukaemia: comparison of oral and intramuscular methotrexate and two doses of radiation.

Serial cranial computed tomograms were carried out in 136 children with acute lymphoblastic leukaemia who were receiving 24 Gy or 18 Gy of cranial irradiation and continuing treatment with doses of methotrexate given weekly orally or intramuscularly. The findings were correlated with treatment varia...

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Bibliographic Details
Main Authors: Chessells, J, Cox, T, Kendall, B, Cavanagh, N, Jannoun, L, Richards, S
Format: Journal article
Language:English
Published: 1990