From Young to Old: Mimicking Neuronal Aging in Directly Converted Neurons from Young Donors

A substantial challenge in human brain aging is to find a suitable model to mimic neuronal aging in vitro as accurately as possible. Using directly converted neurons (iNs) from human fibroblasts is considered a promising tool in human aging since it retains the aging-associated mitochondrial donor s...

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Bibliographic Details
Main Authors: Varghese, N, Grimm, A, Cader, MZ, Eckert, A
Format: Journal article
Language:English
Published: MDPI 2024