A deletion in the gene encoding the CD45 antigen in a patient with SCID.

SCID is a heterogeneous group of hereditary diseases. Mutations in the common gamma-chain (gamma(c)) of cytokine receptors, including those for IL-2, IL-4, IL-7, IL-9, and IL-15, are responsible for an X-linked form of the disease, while mutations of several other genes, including Janus-associated k...

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Bibliographic Details
Main Authors: Tchilian, E, Wallace, D, Wells, R, Flower, DR, Morgan, G, Beverley, P
Format: Journal article
Language:English
Published: 2001