Synthesis and reactivity of novel gamma-phosphate modified ATP analogues.

We hereby present a simple yet novel chemical synthesis of a family of gamma-modified ATPs bearing functional groups on the gamma-phosphate that are amenable to further derivatization by highly selective chemical manipulations (e.g., click chemistry, Staudinger ligations). A preliminary screen of th...

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Bibliographic Details
Main Authors: Lee, SE, Elphick, L, Anderson, A, Bonnac, L, Child, E, Mann, D, Gouverneur, V
Format: Journal article
Language:English
Published: 2009