Membrane-type 1 matrix metalloproteinase cleaves CD44 and promotes cell migration.
Migratory cells including invasive tumor cells frequently express CD44, a major receptor for hyaluronan and membrane-type 1 matrix metalloproteinase (MT1-MMP) that degrades extracellular matrix at the pericellular region. In this study, we demonstrate that MT1-MMP acts as a processing enzyme for CD4...
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Journal article |
| Idioma: | English |
| Publicado: |
2001
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