K(Ca) channel blockers reveal hyperpolarization and relaxation to K+ in rat isolated mesenteric artery.
Raising extracellular K+ concentration ([K+](o)) around mesenteric resistance arteries reverses depolarization and contraction to phenylephrine. As smooth muscle depolarizes and intracellular Ca(2+) and tension increase, this effect of K+ is suppressed, whereas efflux of cellular K+ through Ca(2+)-a...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2002
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