Electrostatics studies and molecular dynamics simulations of a homology model of the Shaker K+ channel pore.

Electrostatics studies and molecular dynamics simulations of a homology model of the Shaker K+ channel pore.

A homology model of the pore domain of the Shaker K+ channel has been constructed using a bacterial K+ channel, KcsA, as a template structure. The model is in agreement with mutagenesis and sequence variability data. A number of structural features are conserved between the two channels, including a...

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Bibliographische Detailangaben
Hauptverfasser:	Ranatunga, K, Law, R, Smith, G, Sansom, MS
Format:	Journal article
Sprache:	English
Veröffentlicht:	2001

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