Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia

Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia

Atrial fibrillation, the most common cardiac arrhythmia, is an important contributor to mortality and morbidity, and particularly to the risk of stroke in humans1. Atrial-tissue fibrosis is a central pathophysiological feature of atrial fibrillation that also hampers its treatment; the underlying mo...

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Bibliographic Details
Main Authors: Moreira, LM, Takawale, A, Hulsurkar, M, Menassa, DA, Antanaviciute, A, Lahiri, SK, Mehta, N, Evans, N, Psarros, C, Robinson, P, Sparrow, A, Gillis, M-A, Ashley, N, Naud, P, Barallobre-Barreiro, J, Theofilatos, K, Lee, A, Norris, M, Clarke, MV, Russell, PK, Casadei, B, Bhattacharya, S, Zajac, JD, Davey, RA, Sirois, M, Mead, A, Simmons, A, Mayr, M, Sayeed, R, Krasopoulos, G, Redwood, C, Channon, KM, Tardif, J-C, Wehrens, X, Nattel, S, Reilly, S
Format: Journal article
Language:English
Published: Nature Research 2020

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