Paracrine signalling by cardiac calcitonin controls atrial fibrogenesis and arrhythmia
Atrial fibrillation, the most common cardiac arrhythmia, is an important contributor to mortality and morbidity, and particularly to the risk of stroke in humans1. Atrial-tissue fibrosis is a central pathophysiological feature of atrial fibrillation that also hampers its treatment; the underlying mo...
Main Authors: | Moreira, LM, Takawale, A, Hulsurkar, M, Menassa, DA, Antanaviciute, A, Lahiri, SK, Mehta, N, Evans, N, Psarros, C, Robinson, P, Sparrow, A, Gillis, M-A, Ashley, N, Naud, P, Barallobre-Barreiro, J, Theofilatos, K, Lee, A, Norris, M, Clarke, MV, Russell, PK, Casadei, B, Bhattacharya, S, Zajac, JD, Davey, RA, Sirois, M, Mead, A, Simmons, A, Mayr, M, Sayeed, R, Krasopoulos, G, Redwood, C, Channon, KM, Tardif, J-C, Wehrens, X, Nattel, S, Reilly, S |
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Format: | Journal article |
Language: | English |
Published: |
Nature Research
2020
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