Oxaliplatin/capecitabine vs oxaliplatin/infusional 5-FU in advanced colorectal cancer: the MRC COIN trial.

BACKGROUND: COIN compared first-line continuous chemotherapy with the same chemotherapy given intermittently or with cetuximab in advanced colorectal cancer (aCRC). METHODS: Choice between oxaliplatin/capecitabine (OxCap) and oxaliplatin/leucovorin (LV)/infusional 5-FU (OxFU) was by physician and pa...

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Bibliographic Details
Main Authors: Madi, A, Fisher, D, Wilson, R, Adams, R, Meade, A, Kenny, S, Nichols, L, Seymour, M, Wasan, H, Kaplan, R, Maughan, T
Format: Journal article
Language:English
Published: 2012