Interleukin-1 and tumour necrosis factor mRNA expression in rheumatoid arthritis: prolonged production of IL-1 alpha.

In rheumatoid arthritis there is a chronic immune and inflammatory reaction which can lead to the destruction of the diseased joint. Cytokine gene expression was studied in synovial cells using cDNA probes specific for human interleukin 1 (IL-1), -alpha and IL-1 beta, tumour necrosis factor (TNF), -...

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Bibliographic Details
Main Authors: Buchan, G, Barrett, K, Turner, M, Chantry, D, Maini, R, Feldmann, M
Format: Journal article
Language:English
Published: 1988