A coarse-grained bacterial cell model for resource-aware analysis and design of synthetic gene circuits

Within a cell, synthetic and native genes compete for expression machinery, influencing cellular process dynamics through resource couplings. Models that simplify competitive resource binding kinetics can guide the design of strategies for countering these couplings. However, in bacteria resource av...

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Bibliographic Details
Main Authors: Sechkar, K, Steel, H, Perrino, G, Stan, G-B
Format: Journal article
Language:English
Published: Springer Nature 2024