OvAd1, a novel, potent, and selective chimeric oncolytic virus developed for ovarian cancer by 3D-directed evolution

Effective therapeutics for ovarian cancer continue to be urgently needed, particularly for chemotherapy-resistant cases. Here we present both a 3D-Matrigel culture-based expansion of our directed evolution method for generation of oncolytic virotherapies and two promising ovarian-cancer targeted onc...

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Bibliographic Details
Main Authors: Kuhn, I, Bauzon, M, Green, N, Seymour, L, Fisher, K, Hermiston, T
Format: Journal article
Language:English
Published: Elsevier 2017