BRD3 and BRD4 BET bromodomain proteins differentially regulate skeletal myogenesis
Myogenic differentiation proceeds through a highly coordinated cascade of gene activation that necessitates epigenomic changes in chromatin structure. Using a screen of small molecule epigenetic probes we identified three compounds which inhibited myogenic differentiation in C2C12 myoblasts; (+)-JQ1...
Автори: | Roberts, T, Etxaniz, U, Dall'Agnese, A, Wu, S, Chiang, C, Brennan, P, Wood, M, Puri, P |
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Формат: | Journal article |
Мова: | English |
Опубліковано: |
Springer Nature
2017
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