The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages.
The cellular response to hypoxia includes the hypoxia-inducible factor-1 (HIF-1)-induced transcription of genes involved in diverse processes such as glycolysis and angiogenesis. Induction of the HIF-regulated genes, as a consequence of the microenvironment or genetic changes, is known to have an im...
প্রধান লেখক: | Talks, K, Turley, H, Gatter, K, Maxwell, P, Pugh, C, Ratcliffe, P, Harris, A |
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বিন্যাস: | Journal article |
ভাষা: | English |
প্রকাশিত: |
2000
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অনুরূপ উপাদানগুলি
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