The SIGLEC14 null allele is associated with Mycobacterium tuberculosis- and BCG-induced clinical and immunologic outcomes

Humans exposed to Mycobacterium tuberculosis (Mtb) have variable susceptibility to tuberculosis (TB) and its outcomes. Siglec-5 and Siglec-14 are members of the sialic-acid binding lectin family that regulate immune responses to pathogens through inhibitory (Siglec-5) and activating (Siglec-14) doma...

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Bibliographic Details
Main Authors: Graustein, A, Horne, D, Fong, J, Schwarz, F, Mefford, H, Peterson, G, Wells, R, Musvosvi, M, Shey, M, Hanekom, W, Hatherill, M, Scriba, T, Thuong, N, Mai, N, Caws, M, Bang, N, Dunstan, S, Thwaites, G, Varki, A, Angata, T, Hawn, T
Format: Journal article
Published: Elsevier 2017